We believe that breakthrough medicines and a coordinated strategy can solve the addiction crisis at scale


OUR MISSION

Here’s what makes CASPR different.

Clinicians, scientists, and informed policy makers agree that addiction is a disease and we are facing a public health emergency. But compared to diseases with comparable public health burdens, like cancer and heart disease, the US invests 95% less towards the development of new treatments for addiction. And unlike our response to other urgent public health crises, like COVID or HIV/AIDS, we are not acting rapidly and with a coordinated focus to get breakthrough medications into the hands of doctors and patients.

CASPR — the Center for Addiction Science, Policy, and Research — is focused on large-scale strategic opportunities in policy and practice that can permanently reduce the cascade of harms from addiction to a fraction of  its current size.

We believe that the addiction crisis, both the new and urgent threats of fentanyl and methamphetamine overdoses and also the older grinding scourges of alcohol and nicotine addiction, can be solved at scale if we bring urgency, political strategy, and coordination to the challenge.

By now, you should be a little skeptical. Addiction is an entrenched multifactorial morass that’s grown much worse over the past decade-- what hasn’t already been tried that could make a big difference over a short time horizon?  We just ask that you read our research and proposals and see if you agree that there’s a dramatically better path available.

CASPR’s goal is to drive system-wide change. We aren’t here to help cope with the addiction crisis or gradually chip away at the problem, we are here to fight it and we are here to win. 


Donate

If you’d like to support our work, you can donate here.  We are a 501c3 tax-deductible non-profit organization, entirely funded by individuals and public foundations.  We have no financial support, directly or indirectly, from pharmaceutical companies.

Why might CASPR be worth your support?  We are a high-impact organization, relentlessly focused on bring a strategic approach to the field of addiction medicine and getting new treatments to patients as soon as possible.   Our background is in startups, tech, science, and medicine-- we are here to move fast and make change at scale.  If you are considering a larger donation, please reach out.  We’d love to tell you more about our approach and operations.
OUR PUBLICATION
Our publication, Recursive Adaptation, has over 5,000 subscribers, primarily researchers and practitioners in addiction medicine. 





SELECTED ARTICLES



FDA standards for addiction medicine studies are discouraging the development of medications   →
Nicholas Reville   November 4, 2024



The Medical Evidence for Using Ozempic and GLP-1s for Addiction   →
Nicholas Reville, Zarinah Agnew, PhD   May 14, 2024

GRACE: Proposing a new GLP-1 based harm reduction strategy →
Nicholas Reville   July 25, 2024

A Federal Moonshot for Better Addiction Medications Can Help Us Escape the Crisis   →


Nicholas Reville   April 14, 2024


"Growing concerns" that Ozempic will disrupt big tobacco, candy companies, and alcohol brands, according to Morgan Stanley   →


Nicholas Reville   April 26, 2024





OUR TEAM

Nicholas Reville
Cofounder, Executive Director
reville@caspr.org
Lindsay Holden
Cofounder, Managing Director
holden@caspr.org

Karam Elabd, MSc
Research Manager, Data Scientist
elabd@caspr.org
Meimei Fong-Minhas
Researcher, Public Health
fong-minhas@caspr.org

Selin Kubali
Researcher, Computational Biology
kubali@caspr.org
Diana Lado Andrew
Public Health Researcher

Divya Saraf
Design Director
saraf@caspr.org
Johanna Einsiedler, MSc
Researcher, Data Scientist
einsiedler@caspr.org


ADVISORY BOARD

Keith Humphreys, OBE PhD
Stanford University

Alex Jutca, MPP
Allegheny County Department of Human Services

Paul Niehaus, PhD
GiveDirectly

Sona Chandra, MPH
Pangea Bio
Morris Birnbaum, MD, PhD
Professor Emeritus, University of Pennsylvania

Ned Nunes, MD
Columbia University

Tom Hudzik, PhD
ALA+ BioPharma Consulting

Maya Durvasula

Stanford University


2024 - Center for Addiction Science, Policy, and Research (CASPR)